Search results for "Immunomodulatory peptide"

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Gastrin: an acid-releasing, proliferative and immunomodulatory peptide?

2010

Gastrin release is affected by gastric inflammatory conditions. Antral G cells respond to inflammatory mediators by increasing gastrin secretion. Accumulating experimental evidence suggests that gastrin exerts immunomodulatory and proinflammatory effects. Gastrin could be a contributing factor to these pathologies, which may constitute a new justification for pharmacological blockade of gastrin action.

medicine.medical_specialtyInflammationdigestive systemProinflammatory cytokineGastric AcidImmunomodulationInternal medicineDrug DiscoveryGastrinsmedicineAnimalsHumansSecretionGastrin-Secreting CellsProtein PrecursorsAntrumGastrinCell ProliferationPharmacologyChemistrydigestive oral and skin physiologyGeneral MedicineBlockadeImmunomodulatory peptideEndocrinologyGastrinomaGastritisReceptors CholecystokininG cellmedicine.symptomhormones hormone substitutes and hormone antagonistsSignal TransductionMini reviews in medicinal chemistry

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